Book By Gustavo Hernández Vidal / DMCA Proteinasas Cisteínicas En Discondroplasia, Osteocondrosis Equina: Inmunolocalización De Catepsina B En Osteoclastos Del Caballo (Spanish Edition)
Muestras de cartílago y hueso subcondral normal y discondroplásico empleadas para éste estudio fueron analizadas inmunohistoquímicamente. Histológicamente, se observó una desorganización celular en los condrocitos de la zona profunda o hipertrófica de las muestras de cartílago discondroplásico. En cambio, en las muestras de cartílago normal se observó la organización columnar característica de esa...
Paperback: 76 pages
Publisher: Editorial Académica Española (August 3, 2013)
Language: Spanish
ISBN-10: 9783659078842
ISBN-13: 978-3659078842
ASIN: 3659078840
Product Dimensions: 5.9 x 0.2 x 8.7 inches
Format: PDF Text djvu book
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zona en caballos jóvenes. La expresión intracelular de la enzima catepsina B fue mayor en las muestras de cartílago discondroplásico que en las normales, lo cual corresponde con la desorganización celular existente en esas muestras. En cuanto a los osteoclastos, no se observó histológicamente alguna diferencia en su organización o fenotipo entre las muestras de cartílago normal o discondroplásico. La expresión de la catepsina B en los osteoclastos se inmunolocalizó en la mayoría de las muestras estudiadas. El hecho de que la expresión de la catepsina B sea mayor en cartílago discondroplásico que en el normal, sugiere que esta enzima, además de participar en el proceso normal de osificación endocondral, juegue un papel importante en la patogénesis de la discondroplasia.
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